tl.design

tl.design#

Functions to design enhancers using CREsted models.

Classes

EnhancerOptimizer

Class to optimize the mutated sequence based on the original prediction.

Functions

derive_intermediate_sequences(...)

Derive the intermediate sequences from the enhancer design intermediate dictionary.

in_silico_evolution(n_mutations, target, model)

Create synthetic enhancers for a specified class using in silico evolution (ISE).

motif_insertion(patterns, model, target[, ...])

Create synthetic enhancers using motif insertions.